Carbamic acid,N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-,5-thiazolylmethyl ester
(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane
CAS: 144164-11-4
Molecular Formula: C23H27N3O3S
Carbamic acid,N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-,5-thiazolylmethyl ester - Names and Identifiers
Carbamic acid,N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-,5-thiazolylmethyl ester - Physico-chemical Properties
| Molecular Formula | C23H27N3O3S |
| Molar Mass | 425.54 |
| Density | 1.251±0.06 g/cm3(Predicted) |
| Boling Point | 656.1±55.0 °C(Predicted) |
| Flash Point | 350.6°C |
| Vapor Presure | 4.17E-18mmHg at 25°C |
| Appearance | pale yellow oily |
| pKa | 11.48±0.46(Predicted) |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
| Refractive Index | 1.619 |
Carbamic acid,N-[(1S,2S,4S)-4-amino-2-hydroxy-5-phenyl-1-(phenylmethyl)pentyl]-,5-thiazolylmethyl ester - Introduction
(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1, also known as thiazole hexane dibenzyloxycarbonyl proline (Fmoc). The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White crystalline solid
-Molecular formula: C32H32N4O4S
-Molecular weight: 576.68g/mol
-Melting Point: 198-202 ° C
-Solubility: Soluble in organic solvents such as methanol, dichloromethane and ethanol, slightly soluble in water
Use:
- Fmoc proline is a commonly used Amine protecting group, which is widely used in the synthesis and modification of peptides in solid phase synthesis.
-It can react with amino acid residues by forming imides, and deprotect when needed, so that the peptide chain remains intact during the synthesis process.
- Fmoc proline is also used in peptide chemistry research, drug discovery, and biomedical applications.
Method:
(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1, calcium can be obtained by synthesis. Specific laws include:
1. Chemical synthesis using related compounds.
2. The structure of the product was confirmed by mass spectrometry.
Safety Information:
Fmoc Proline has low toxicity under normal operating conditions, but the following safety precautions still need to be paid attention:
-Avoid inhalation or skin contact. Wear protective gloves and face mask.
-Maintain well-ventilated laboratory conditions during operation.
-For accidental contact, rinse immediately with plenty of water and seek medical advice.
-Keep dry during storage and avoid contact with oxidants and strong acids.
Nature:
-Appearance: White crystalline solid
-Molecular formula: C32H32N4O4S
-Molecular weight: 576.68g/mol
-Melting Point: 198-202 ° C
-Solubility: Soluble in organic solvents such as methanol, dichloromethane and ethanol, slightly soluble in water
Use:
- Fmoc proline is a commonly used Amine protecting group, which is widely used in the synthesis and modification of peptides in solid phase synthesis.
-It can react with amino acid residues by forming imides, and deprotect when needed, so that the peptide chain remains intact during the synthesis process.
- Fmoc proline is also used in peptide chemistry research, drug discovery, and biomedical applications.
Method:
(2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1, calcium can be obtained by synthesis. Specific laws include:
1. Chemical synthesis using related compounds.
2. The structure of the product was confirmed by mass spectrometry.
Safety Information:
Fmoc Proline has low toxicity under normal operating conditions, but the following safety precautions still need to be paid attention:
-Avoid inhalation or skin contact. Wear protective gloves and face mask.
-Maintain well-ventilated laboratory conditions during operation.
-For accidental contact, rinse immediately with plenty of water and seek medical advice.
-Keep dry during storage and avoid contact with oxidants and strong acids.
Last Update：2024-04-09 02:00:42
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Product Name: (2S,3S,5S)-5-Amino-2-(N-((5-thiazolyl)-methoxycarbonyl)amino)-1,6-diphenyl-3-hydroxyhexane Visit Supplier Webpage Request for quotation
CAS: 144164-11-4
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